Cargando…

Cefiderocol is an effective topical monotherapy for experimental extensively-drug resistant Pseudomonas aeruginosa keratitis

PURPOSE: To test cefiderocol, a siderophore-cephalosporin antibiotic for topical monotherapy treatment of experimental extensively drug resistant (XDR) Pseudomonas aeruginosa keratitis. DESIGN: Preclinical study. SUBJECTS AND CONTROLS: Deidentified P. aeruginosa keratitis isolates, XDR P. aeruginosa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Romanowski, Eric G., Mumper, Sonya M., Shanks, Hazel Q., Yates, Kathleen A., Mandell, Jonathan B., Zegans, Michael E., Shanks, Robert M. Q.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491197/ https://www.ncbi.nlm.nih.gov/pubmed/37693441 http://dx.doi.org/10.1101/2023.08.31.555778

Ejemplares similares

Rise in frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021
por: Shanks, Robert M. Q., et al.
Publicado: (2023)

A rise in the frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021
por: Shanks, Robert M. Q., et al.
Publicado: (2023)

Multifunctional Monoclonal Antibody Targeting Pseudomonas aeruginosa Keratitis in Mice
por: Hebert, Wesley, et al.
Publicado: (2020)

Predatory Bacteria can Reduce Pseudomonas aeruginosa Induced Corneal Perforation and Proliferation in a Rabbit Keratitis Model
por: Romanowski, Eric G., et al.
Publicado: (2023)

Topical Astodrimer Sodium, a Non-Toxic Polyanionic Dendrimer, Demonstrates Antiviral Activity in an Experimental Ocular Adenovirus Infection Model
por: Romanowski, Eric G., et al.
Publicado: (2021)

Successful use of prolonged cefiderocol monotherapy for the treatment of a complex pleural abscess caused by extensively drug-resistant (XDR) Pseudomonas aeruginosa
por: Brookfield, Charlotte, et al.
Publicado: (2023)

Intra-ocular Predation of Fluoroquinolone-Resistant Pseudomonas aeruginosa and Serratia marcescens by Predatory Bacteria
por: Romanowski, Eric G., et al.
Publicado: (2023)

In Vitro Activity of Cefiderocol against Extensively Drug-Resistant Pseudomonas aeruginosa: CANWARD, 2007 to 2019
por: Karlowsky, James A., et al.
Publicado: (2022)

Progressive in vivo development of resistance to cefiderocol in Pseudomonas aeruginosa
por: Sadek, Mustafa, et al.
Publicado: (2022)

The in vitro Evaluation of the Activity of COVID-19 Antiviral Drugs Against Adenovirus
por: Romanowski, Eric G, et al.
Publicado: (2021)

Pseudomonas aeruginosa Keratitis in Mice: Effects of Topical Bacteriophage KPP12 Administration
por: Fukuda, Ken, et al.
Publicado: (2012)

Cefiderocol for treatment of an empyema due to extensively drug-resistant Pseudomonas aeruginosa: Clinical observations and susceptibility testing considerations
por: Kufel, Wesley D., et al.
Publicado: (2020)

Serrated Margins in Pseudomonas aeruginosa Keratitis
por: Ishikawa, Eri, et al.
Publicado: (2013)

Recalcitrant Pseudomonas Aeruginosa Keratitis with Hyphaema
por: Chan, Amy, et al.
Publicado: (2021)

Multi-drug resistant Pseudomonas aeruginosa keratitis and its effective treatment with topical colistimethate
por: Chatterjee, Samrat, et al.
Publicado: (2016)

Pseudomonas aeruginosa Keratitis in Rats: Study of the Effect of Topical 5% Hesperidin Practice on Healing
por: Utlu, Bahadır, et al.
Publicado: (2023)

Chlorhexidine Monotherapy with Adjunctive Topical Corticosteroids for Acanthamoeba Keratitis
por: Rahimi, Firoozeh, et al.
Publicado: (2015)

Proteomic analysis of keratitis-associated Pseudomonas aeruginosa
por: Sewell, Abby, et al.
Publicado: (2014)

Combination of phage therapy and cefiderocol to successfully treat Pseudomonas aeruginosa cranial osteomyelitis
por: Simner, Patricia J., et al.
Publicado: (2022)

Activation of the lectin pathway of complement in experimental human keratitis with Pseudomonas aeruginosa
por: Osthoff, Michael, et al.
Publicado: (2014)

An unusual case of Acanthamoeba Polyphaga and Pseudomonas Aeruginosa keratitis
por: Hong, Jiaxu, et al.
Publicado: (2014)

1246. Clinical isolates of Pseudomonas aeruginosa Harbor Preexisting Changes in TonB-dependent Receptors Associated with Decreased Susceptibility to Cefiderocol
por: Egge, Stephanie L, et al.
Publicado: (2021)

Education: A compassionate use of cefiderocol to treat osteomyelitis caused by an XDR Pseudomonas aeruginosa
por: Chavda, A, et al.
Publicado: (2021)

Cefiderocol Activity Against Clinical Pseudomonas aeruginosa Isolates Exhibiting Ceftolozane-Tazobactam Resistance
por: Simner, Patricia J, et al.
Publicado: (2021)

Pseudomonas aeruginosa Contact-Dependent Growth Inhibition Plays Dual Role in Host-Pathogen Interactions
por: Melvin, Jeffrey A., et al.
Publicado: (2017)

P44 Nosocomial neurosurgical meningitis due to XDR Pseudomonas aeruginosa: clinical experience with cefiderocol
por: Stevenson, D. R., et al.
Publicado: (2022)

648. Cefiderocol as Rescue Therapy for Pseudomonas aeruginosa and Other Difficult-To-Treat Gram-Negative Infections
por: Chou, Andrew, et al.
Publicado: (2022)

Cefiderocol Treatment for Patients with Multidrug- and Carbapenem-Resistant Pseudomonas aeruginosa Infections in the Compassionate Use Program
por: Satlin, Michael J., et al.
Publicado: (2023)

Pseudomonas aeruginosa keratitis misdiagnosed as fungal keratitis by in vivo confocal microscopy: a case report
por: Hong, Jiaxu, et al.
Publicado: (2014)

2750. Pseudomonas aeruginosa infections treated with cefiderocol: associations of site of infection and time to first dose with outcomes in PROVE (Retrospective Cefiderocol Chart Review) Study
por: Marcella, Stephen, et al.
Publicado: (2023)

Impact of Microbiota on Resistance to Ocular Pseudomonas aeruginosa-Induced Keratitis
por: Kugadas, Abirami, et al.
Publicado: (2016)

Siderophore Cephalosporin Cefiderocol Utilizes Ferric Iron Transporter Systems for Antibacterial Activity against Pseudomonas aeruginosa
por: Ito, Akinobu, et al.
Publicado: (2016)

Lithium chloride promotes host resistance against Pseudomonas aeruginosa keratitis
por: Chen, Kang, et al.
Publicado: (2013)

Glycyrrhizin Reduces HMGB1 and Bacterial Load in Pseudomonas aeruginosa Keratitis
por: Ekanayaka, Sandamali A., et al.
Publicado: (2016)

Pseudomonas aeruginosa Keratitis: Protease IV and PASP as Corneal Virulence Mediators
por: O’Callaghan, Richard, et al.
Publicado: (2019)

Bilateral Pseudomonas aeruginosa keratitis as presenting feature in an infant of cystic fibrosis
por: Lakshmipathy, Meena, et al.
Publicado: (2022)

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis
por: Zhang, Bi Ning, et al.
Publicado: (2023)

Activity of Cefiderocol Against Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumannii Endemic to Medical Centers in New York City
por: Iregui, Alejandro, et al.
Publicado: (2020)

Real-life experience with compassionate use of cefiderocol for difficult-to-treat resistant Pseudomonas aeruginosa (DTR-P) infections
por: Meschiari, Marianna, et al.
Publicado: (2021)

Severe Keratitis Caused by Pseudomonas aeruginosa Successfully Treated with Ceftazidime Associated with Acetazolamide
por: Hue, Benoit, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_5n4s8svtnik4301ckk8ivm3i27