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Full-length direct RNA sequencing reveals widespread RNA decay upon cellular stress

Cells respond and adapt to endogenous and exogenous stressors by activating stress response pathways that restore cellular homeostasis. The capacity of cells to respond to stress declines with age and has been associated with disease. However, the changes in cytoplasmic RNA metabolism during the cel...

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Detalles Bibliográficos
Autores principales: Dar, Showkat A., Malla, Sulochan, Lee, Christopher T., Payea, Matthew J., Martin, Jessica, Khandeshi, Aditya J., Martindale, Jennifer L., Belair, Cedric, Maragkakis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491209/
https://www.ncbi.nlm.nih.gov/pubmed/37693505
http://dx.doi.org/10.1101/2023.08.31.555629