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Antibody effector functions are required for broad and potent protection of neonates from herpes simplex virus infection

The failure of multiple herpes simplex virus (HSV) vaccine candidates that induce neutralizing antibody responses raises the hypothesis that other activities, such as Fc domain-dependent effector functions, may be critical for protection. While neonatal HSV (nHSV) infection result in mortality and l...

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Detalles Bibliográficos
Autores principales: Slein, Matthew D., Backes, Iara M., Garland, Callaghan R., Kelkar, Natasha S., Leib, David A., Ackerman, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491243/
https://www.ncbi.nlm.nih.gov/pubmed/37693377
http://dx.doi.org/10.1101/2023.08.29.555423

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