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Characterization of erythroferrone oligomerization and its impact on BMP antagonism

Hepcidin, a peptide hormone that negatively regulates iron metabolism, is expressed by bone morphogenetic protein (BMP) signaling. Erythroferrone (ERFE) is an extracellular protein that binds and inhibits BMP ligands, thus positively regulating iron import by indirectly suppressing hepcidin. This al...

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Detalles Bibliográficos
Autores principales:	Mast, Jacob F, Leach, Edmund A E, Thompson, Thomas B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491252/ https://www.ncbi.nlm.nih.gov/pubmed/37693455 http://dx.doi.org/10.1101/2023.09.01.555965

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