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Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop
Although the αC-β4 loop is a stable feature of all protein kinases, the importance of this motif as a conserved element of secondary structure, as well as its links to the hydrophobic architecture of the kinase core, has been underappreciated. We first review the motif and then describe how it is li...
Autores principales: | Wu, Jian, Jonniya, Nisha A., Hirakis, Sophia P., Olivieri, Cristina, Veglia, Gianluigi, Kornev, Alexandr P., Taylor, Susan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491255/ https://www.ncbi.nlm.nih.gov/pubmed/37693538 http://dx.doi.org/10.1101/2023.08.31.555822 |
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