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Dissociation process of polyalanine aggregates by free electron laser irradiation

Polyalanine (polyA) disease-causative proteins with an expansion of alanine repeats can be aggregated. Although curative treatments for polyA diseases have not been explored, the dissociation of polyA aggregates likely reduces the cytotoxicity of polyA. Mid-infrared free electron laser (FEL) success...

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Detalles Bibliográficos
Autores principales:	Okumura, Hisashi, Itoh, Satoru G., Zen, Heishun, Nakamura, Kazuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491298/ https://www.ncbi.nlm.nih.gov/pubmed/37683014 http://dx.doi.org/10.1371/journal.pone.0291093

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