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Engineering Quorum Quenching Acylases with Improved Kinetic and Biochemical Properties
Many Gram-negative bacteria respond to N-acyl-L-homoserine lactone (AHL) signals to coordinate phenotypes such as biofilm formation and virulence factor production. Quorum-quenching enzymes, such as acylases, chemically degrade AHL signals, prevent signal reception by bacteria, and inhibit undesirab...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491313/ https://www.ncbi.nlm.nih.gov/pubmed/37693529 http://dx.doi.org/10.1101/2023.09.01.555929 |