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A rapid and dynamic role for FMRP in the plasticity of adult neurons

Fragile X syndrome (FXS) is a neuro-developmental disorder caused by silencing Fmr1, which encodes the RNA-binding protein FMRP. Although Fmr1 is expressed in adult neurons, it has been challenging to separate acute from chronic effects of loss of Fmr1 in models of FXS. We have used the precision of...

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Detalles Bibliográficos
Autores principales: Gundermann, Daniel G., Lymer, Seana, Blau, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491314/
https://www.ncbi.nlm.nih.gov/pubmed/37693612
http://dx.doi.org/10.1101/2023.09.01.555985