Predicted broadly neutralizing antibody (bnAb) resistance and associated envelope characteristics of adults with HIV-1 seroconversion in Botswana

We used HIV-1C sequences to predict (in silico) resistance to 33 known broadly neutralizing antibodies (bNAbs) and evaluate the different HIV-1 env characteristics that may affect virus neutralization. We analyzed proviral sequences from adults with documented HIV-1 seroconversion (N=140) in Botswan...

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Detalles Bibliográficos
Autores principales: Moraka, Natasha Onalenna, Choga, Wonderful T., Pema, Marea N., Chawawa, Moses K., Gobe, Irene, Mokomane, Margaret, Bareng, Ontlametse T., Bhebhe, Lynnette, Kelentse, Nametso, Mulenga, Graceful, Pretorius-Holme, Molly, Mohammed, Terence, Koofhethile, Catherine K., Makhema, Joseph M., Shapiro, Roger, Lockman, Shahin, Moyo, Sikhulile, Gaseitsiwe, Simani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491331/
https://www.ncbi.nlm.nih.gov/pubmed/37693564
http://dx.doi.org/10.21203/rs.3.rs-3194948/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491331/
https://www.ncbi.nlm.nih.gov/pubmed/37693564
http://dx.doi.org/10.21203/rs.3.rs-3194948/v1

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