Association of Common and Rare Variants with Alzheimer’s Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer’s Disease Sequencing Project

Alzheimer’s Disease (AD) is a common disorder of the elderly that is both highly heritable and genetically heterogeneous. Here, we investigated the association between AD and both common variants and aggregates of rare coding and noncoding variants in 13,371 individuals of diverse ancestry with whol...

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Detalles Bibliográficos
Autores principales: Lee, Wan-Ping, Choi, Seung Hoan, Shea, Margaret G, Cheng, Po-Liang, Dombroski, Beth A, Pitsillides, Achilleas N, Heard-Costa, Nancy L, Wang, Hui, Bulekova, Katia, Kuzma, Amanda B, Leung, Yuk Yee, Farrell, John J, Lin, Honghuang, Naj, Adam, Blue, Elizabeth E, Nusetor, Frederick, Wang, Dongyu, Boerwinkle, Eric, Bush, William S, Zhang, Xiaoling, De Jager, Philip L, Dupuis, Josée, Farrer, Lindsay A, Fornage, Myriam, Martin, Eden, Pericak-Vance, Margaret, Seshadri, Sudha, Wijsman, Ellen M, Wang, Li-San, Schellenberg, Gerard D, Destefano, Anita L, Haines, Jonathan L, Peloso, Gina M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491367/
https://www.ncbi.nlm.nih.gov/pubmed/37693521
http://dx.doi.org/10.1101/2023.09.01.23294953

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