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Prioritizing Cardiovascular Disease-Associated Variants Altering NKX2–5 Binding through an Integrative Computational Approach
Cardiovascular diseases (CVDs) are the leading cause of death worldwide and are heavily influenced by genetic factors. Genome-wide association studies (GWAS) have mapped > 90% of CVD-associated variants within the non-coding genome, which can alter the function of regulatory proteins, like transc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491373/ https://www.ncbi.nlm.nih.gov/pubmed/37693486 http://dx.doi.org/10.1101/2023.09.01.23294951 |