Prioritizing Cardiovascular Disease-Associated Variants Altering NKX2–5 Binding through an Integrative Computational Approach

Cardiovascular diseases (CVDs) are the leading cause of death worldwide and are heavily influenced by genetic factors. Genome-wide association studies (GWAS) have mapped > 90% of CVD-associated variants within the non-coding genome, which can alter the function of regulatory proteins, like transc...

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Detalles Bibliográficos
Autores principales: Peña-Martínez, Edwin G., Pomales-Matos, Diego A., Rivera-Madera, Alejandro, Messon-Bird, Jean L., Medina-Feliciano, Joshua G., Sanabria-Alberto, Leandro, Barreiro-Rosario, Adriana C., Rodriguez-Rios, Jessica M., Rodríguez-Martínez, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491373/
https://www.ncbi.nlm.nih.gov/pubmed/37693486
http://dx.doi.org/10.1101/2023.09.01.23294951

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