3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

IMPORTANCE: The prevalence of childhood obesity is increasing worldwide, along with the associated common comorbidities of type 2 diabetes and cardiovascular disease in later life. Motivated by evidence for a strong genetic component, our prior genome-wide association study (GWAS) efforts for childh...

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Detalles Bibliográficos
Autores principales: Trang, Khanh B., Pahl, Matthew C., Pippin, James A., Su, Chun, Littleton, Sheridan H., Sharma, Prabhat, Kulkarni, Nikhil N., Ghanem, Louis R., Terry, Natalie A., O’Brien, Joan M., Wagley, Yadav, Hankenson, Kurt D., Jermusyk, Ashley, Hoskins, Jason W., Amundadottir, Laufey T., Xu, Mai, Brown, Kevin M, Anderson, Stewart A., Yang, Wenli, Titchenell, Paul M., Seale, Patrick, Cook, Laura, Levings, Megan K., Zemel, Babette S., Chesi, Alessandra, Wells, Andrew D., Grant, Struan F.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491377/
https://www.ncbi.nlm.nih.gov/pubmed/37693606
http://dx.doi.org/10.1101/2023.08.30.23294092

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