Distinct biological signature and modifiable risk factors underly the comorbidity between major depressive disorder and cardiovascular disease

Major depressive disorder (MDD) and cardiovascular disease (CVD) are often comorbid, resulting in excess morbidity and mortality. Using genetic data, this study elucidates biological mechanisms, key risk factors, and causal pathways underlying the comorbidity. We show that CVDs share a large proport...

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Detalles Bibliográficos
Autores principales: Bergstedt, Jacob, Pasman, Joëlle A., Ma, Ziyan, Harder, Arvid, Yao, Shuyang, Parker, Nadine, Treur, Jorien L., Smit, Dirk J.A., Frei, Oleksandr, Shadrin, Alexey, Meijsen, Joeri J., Shen, Qing, Tornvall, Per, Buil, Alfonso, Werge, Thomas, Hjerling-Leffler, Jens, Als, Thomas D., Børglum, Anders D., Lewis, Cathryn M., McIntosh, Andrew M., Valdimarsdóttir, Unnur A., Andreassen, Ole A., Sullivan, Patrick F., Lu, Yi, Fang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491387/
https://www.ncbi.nlm.nih.gov/pubmed/37693619
http://dx.doi.org/10.1101/2023.09.01.23294931

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