MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

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The molecular circadian clock, which controls rhythmic 24-hour oscillation of genes, proteins, and metabolites in healthy tissues, is disrupted across many human cancers. Deregulated expression of the MYC oncoprotein has been shown to alter expression of molecular clock genes, leading to a disruptio...

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Detalles Bibliográficos
Autores principales: Cazarin, Juliana, DeRollo, Rachel E., Shahidan, Siti Noor Ain Binti Ahmad, Burchett, Jamison B., Mwangi, Daniel, Krishnaiah, Saikumari, Hsieh, Annie L., Walton, Zandra E., Brooks, Rebekah, Mello, Stephano S., Weljie, Aalim M., Dang, Chi V., Altman, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491404/
https://www.ncbi.nlm.nih.gov/pubmed/37639465
http://dx.doi.org/10.1371/journal.pgen.1010904
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