Cargando…

Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens

Adoptive cell transfer of tumor-infiltrating lymphocytes (TIL) can mediate durable complete responses in some patients with common epithelial cancers but does so infrequently. A better understanding of T-cell responses to neoantigens and tumor-related immune evasion mechanisms requires having the au...

Descripción completa

Detalles Bibliográficos
Autores principales: Parikh, Anup Y., Masi, Robert, Gasmi, Billel, Hanada, Ken-ichi, Parkhurst, Maria, Gartner, Jared, Sindiri, Sivasish, Prickett, Todd, Robbins, Paul, Zacharakis, Nikolaos, Beshiri, Mike, Kelly, Kathleen, Rosenberg, Steven A., Yang, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491521/
https://www.ncbi.nlm.nih.gov/pubmed/37368077
http://dx.doi.org/10.1007/s00262-023-03476-6