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Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens
Adoptive cell transfer of tumor-infiltrating lymphocytes (TIL) can mediate durable complete responses in some patients with common epithelial cancers but does so infrequently. A better understanding of T-cell responses to neoantigens and tumor-related immune evasion mechanisms requires having the au...
Autores principales: | Parikh, Anup Y., Masi, Robert, Gasmi, Billel, Hanada, Ken-ichi, Parkhurst, Maria, Gartner, Jared, Sindiri, Sivasish, Prickett, Todd, Robbins, Paul, Zacharakis, Nikolaos, Beshiri, Mike, Kelly, Kathleen, Rosenberg, Steven A., Yang, James C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491521/ https://www.ncbi.nlm.nih.gov/pubmed/37368077 http://dx.doi.org/10.1007/s00262-023-03476-6 |
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