Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription

The second messenger cyclic AMP regulates many nuclear processes including transcription, pre-mRNA splicing and mitosis. While most functions are attributed to protein kinase A, accumulating evidence suggests that not all nuclear cyclic AMP-dependent effects are mediated by this kinase, implying tha...

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Detalles Bibliográficos
Autores principales: Iannucci, Liliana Felicia, D’Erchia, Anna Maria, Picardi, Ernesto, Bettio, Daniela, Conca, Filippo, Surdo, Nicoletta Concetta, Di Benedetto, Giulietta, Musso, Deborah, Arrigoni, Cristina, Lolicato, Marco, Vismara, Mauro, Grisan, Francesca, Salviati, Leonardo, Milanesi, Luciano, Pesole, Graziano, Lefkimmiatis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491619/
https://www.ncbi.nlm.nih.gov/pubmed/37684224
http://dx.doi.org/10.1038/s41467-023-41088-x

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