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PCSK9 and the nervous system: a no-brainer?
In the past 20 years, PCSK9 has been shown to play a pivotal role in LDL cholesterol metabolism and cardiovascular health by inducing the lysosomal degradation of the LDL receptor. PCSK9 was discovered by the cloning of genes up-regulated after apoptosis induced by serum deprivation in primary cereb...
Autores principales: | Jaafar, Ali K., Techer, Romuald, Chemello, Kévin, Lambert, Gilles, Bourane, Steeve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491654/ https://www.ncbi.nlm.nih.gov/pubmed/37586604 http://dx.doi.org/10.1016/j.jlr.2023.100426 |
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