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The role of the Cx43/Cx45 gap junction voltage gating on wave propagation and arrhythmogenic activity in cardiac tissue

Gap junctions (GJs) formed of connexin (Cx) protein are the main conduits of electrical signals in the heart. Studies indicate that the transitional zone of the atrioventricular (AV) node contains heterotypic Cx43/Cx45 GJ channels which are highly sensitive to transjunctional voltage (V(j)). To inve...

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Detalles Bibliográficos
Autores principales: Maciunas, Kestutis, Snipas, Mindaugas, Kraujalis, Tadas, Kraujalienė, Lina, Panfilov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491658/
https://www.ncbi.nlm.nih.gov/pubmed/37684404
http://dx.doi.org/10.1038/s41598-023-41796-w

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