Exacerbated response to oxidative stress in the Retinitis Pigmentosa Cerkl(KD/KO) mouse model triggers retinal degeneration pathways upon acute light stress

The retina is particularly vulnerable to genetic and environmental alterations that generate oxidative stress and cause cellular damage in photoreceptors and other retinal neurons, eventually leading to cell death. CERKL (CERamide Kinase-Like) mutations cause Retinitis Pigmentosa and Cone-Rod Dystro...

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Detalles Bibliográficos
Autores principales: García-Arroyo, Rocío, Domènech, Elena B., Herrera-Úbeda, Carlos, Asensi, Miguel A., Núñez de Arenas, Cristina, Cuezva, José M., Garcia-Fernàndez, Jordi, Pallardó, Federico V., Mirra, Serena, Marfany, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491808/
https://www.ncbi.nlm.nih.gov/pubmed/37660443
http://dx.doi.org/10.1016/j.redox.2023.102862

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