Redefining precision radiotherapy through liquid biopsy

Precision radiotherapy refers to the ability to deliver radiation doses with sub-millimetre accuracy. It does not however consider individual variation in tumour or normal tissue response, failing to maximise tumour control and minimise toxicity. Combining precise delivery with personalised dosing,...

Descripción completa

Detalles Bibliográficos
Autores principales: McLaren, D. B., Aitman, T. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491827/
https://www.ncbi.nlm.nih.gov/pubmed/37598284
http://dx.doi.org/10.1038/s41416-023-02398-5
_version_ 1785104142401798144
author McLaren, D. B.
Aitman, T. J.
author_facet McLaren, D. B.
Aitman, T. J.
author_sort McLaren, D. B.
collection PubMed
description Precision radiotherapy refers to the ability to deliver radiation doses with sub-millimetre accuracy. It does not however consider individual variation in tumour or normal tissue response, failing to maximise tumour control and minimise toxicity. Combining precise delivery with personalised dosing, through analysis of cell-free DNA, would redefine precision in radiotherapy.
format Online
Article
Text
id pubmed-10491827
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-104918272023-09-10 Redefining precision radiotherapy through liquid biopsy McLaren, D. B. Aitman, T. J. Br J Cancer Perspective Precision radiotherapy refers to the ability to deliver radiation doses with sub-millimetre accuracy. It does not however consider individual variation in tumour or normal tissue response, failing to maximise tumour control and minimise toxicity. Combining precise delivery with personalised dosing, through analysis of cell-free DNA, would redefine precision in radiotherapy. Nature Publishing Group UK 2023-08-19 2023-10-05 /pmc/articles/PMC10491827/ /pubmed/37598284 http://dx.doi.org/10.1038/s41416-023-02398-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Perspective
McLaren, D. B.
Aitman, T. J.
Redefining precision radiotherapy through liquid biopsy
title Redefining precision radiotherapy through liquid biopsy
title_full Redefining precision radiotherapy through liquid biopsy
title_fullStr Redefining precision radiotherapy through liquid biopsy
title_full_unstemmed Redefining precision radiotherapy through liquid biopsy
title_short Redefining precision radiotherapy through liquid biopsy
title_sort redefining precision radiotherapy through liquid biopsy
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491827/
https://www.ncbi.nlm.nih.gov/pubmed/37598284
http://dx.doi.org/10.1038/s41416-023-02398-5
work_keys_str_mv AT mclarendb redefiningprecisionradiotherapythroughliquidbiopsy
AT aitmantj redefiningprecisionradiotherapythroughliquidbiopsy

Ejemplares similares