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Immunogenicity and protective efficacy of human metapneumovirus virus-like particles produced by a recombinant baculovirus in mice
BACKGROUND: Human metapneumovirus (HMPV) causes respiratory tract infections among infant, elderly, and immunocompromised patients, with significant mortality. Currently no licensed vaccines or therapeutic agents of HMPV exist. METHODS: HMPV virus-like particle (VLP) was constructed by co-expressing...
Autores principales: | Ma, Fenlian, Chen, Aijun, Yao, Lihong, Gao, Hanchun, Zhang, Qian, Hou, Wenzhe, Zheng, Lishu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491852/ https://www.ncbi.nlm.nih.gov/pubmed/37657510 http://dx.doi.org/10.1016/j.virusres.2023.199215 |
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