Loss of GATA6-mediated up-regulation of UTX promotes pancreatic tumorigenesis and progression

Ubiquitously transcribed tetratricopeptide repeat on chromosome X (UTX), also known as lysine (K)-specific demethylase 6A (KDM6A), functions as a tumor suppressor gene or oncogene depending on the tumor type and context. However, its tumor-suppressive mechanisms remain largely unknown. Here, we inve...

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Detalles Bibliográficos
Autores principales: Zhang, Hui-Qing, Kong, Fanyang, Kong, Xiangyu, Jiang, Tingting, Ma, Muyuan, Zheng, Shaojiang, Guo, Junli, Xie, Keping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491869/
https://www.ncbi.nlm.nih.gov/pubmed/37692474
http://dx.doi.org/10.1016/j.gendis.2023.01.019

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