The Wnt-dependent and Wnt-independent functions of BCL9 in development, tumorigenesis, and immunity: Implications in therapeutic opportunities

B-cell CLL/lymphoma 9 (BCL9) is considered a key developmental regulator and a well-established oncogenic driver in multiple cancer types, mainly through potentiating the Wnt/β-catenin signaling. However, increasing evidences indicate that BCL9 also plays multiple Wnt-independent roles. Herein, we s...

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Detalles Bibliográficos
Autores principales: Wu, Minjie, Dong, Heng, Xu, Chao, Sun, Mengqing, Gao, Haojin, Bu, Fangtian, Chen, Jianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491870/
https://www.ncbi.nlm.nih.gov/pubmed/37692512
http://dx.doi.org/10.1016/j.gendis.2023.03.012

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