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RSPO2 as Wnt signaling enabler: Important roles in cancer development and therapeutic opportunities
R-spondins are secretory proteins localized in the endoplasmic reticulum and Golgi bodies and are processed through the secretory pathway. Among the R-spondin family, RSPO2 has emanated as a novel regulator of Wnt signaling, which has now been acknowledged in numerous in vitro and in vivo studies. C...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chongqing Medical University
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491879/ https://www.ncbi.nlm.nih.gov/pubmed/37692504 http://dx.doi.org/10.1016/j.gendis.2023.01.013 |