Vitamin A deficiency suppresses CEACAM1 to impair colonic epithelial barrier function via downregulating microbial-derived short-chain fatty acids

Vitamin A (VA) plays an essential role in modulating both the gut microbiota and gut barrier function. Short-chain fatty acids (SCFAs), as metabolites of the gut microbiota, protect the physiological intestinal barrier; however, they are compromised when VA is deficient. Thus, there is an urgent nee...

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Detalles Bibliográficos
Autores principales: Yan, Junyan, Xiao, Lu, Feng, Di, Chen, Baolin, Yang, Ting, Tong, Bei, Luo, Ruifang, Wang, Yuting, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491915/
https://www.ncbi.nlm.nih.gov/pubmed/37692511
http://dx.doi.org/10.1016/j.gendis.2023.03.032

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