Severe Immune-Mediated Colitis Induced by Checkpoint Inhibitors in an Adolescent With Lynch Syndrome

Lynch syndrome is a hereditary colorectal cancer caused by mutations in DNA mismatch repair genes. Immune checkpoint therapies have shown promise in treating Lynch syndrome-associated cancers but can lead to immune-related adverse events, such as colitis. In this report, we present a severe case of...

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Detalles Bibliográficos
Autores principales: Lee, Rachel V, Melstrom, Kurt A, Mannan, Rifat, Idos, Gregory E, Kidambi, Trilokesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491925/
https://www.ncbi.nlm.nih.gov/pubmed/37692727
http://dx.doi.org/10.7759/cureus.43246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491925/
https://www.ncbi.nlm.nih.gov/pubmed/37692727
http://dx.doi.org/10.7759/cureus.43246

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