Cargando…
Gluteal Mystery: A Case Report of Superficial CD34-Positive Fibroblastic Tumor
The case at hand involves a 25-year-old woman suffering from a gradual enlargement of a gluteal mass over a five-year period. This rare medical condition is classified as superficial CD34-positive fibroblastic tumor (SCPFT), an intermediate form of mesenchymal malignancy, originally identified in me...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491928/ https://www.ncbi.nlm.nih.gov/pubmed/37692690 http://dx.doi.org/10.7759/cureus.43236 |
_version_ | 1785104166288359424 |
---|---|
author | Ba-shammakh, Saleh A Almaletti, Motasem Hasan, Mohammad M Hijazi, Eman |
author_facet | Ba-shammakh, Saleh A Almaletti, Motasem Hasan, Mohammad M Hijazi, Eman |
author_sort | Ba-shammakh, Saleh A |
collection | PubMed |
description | The case at hand involves a 25-year-old woman suffering from a gradual enlargement of a gluteal mass over a five-year period. This rare medical condition is classified as superficial CD34-positive fibroblastic tumor (SCPFT), an intermediate form of mesenchymal malignancy, originally identified in medical literature in 2014. Initial physical examination revealed a 10 x 10 cm lump in the right upper gluteal region. Magnetic resonance imaging demonstrated a well-circumscribed lesion within the right gluteus maximus muscle. The patient had the lump removed surgically. Examination under a microscope revealed tumor cells with extensive pleomorphism, high cytokeratin (CK) and CD34 positivity, and a low Ki67 index, all of which are consistent with SCPFT. Postoperatively, the patient showed marked improvement, and ongoing monitoring was initiated due to the potential for local recurrence. This case reinforces the importance of considering SCPFT in the differential diagnosis of soft tissue masses, emphasizing the role of immunohistochemical staining in reaching a correct diagnosis. Given the rarity of SCPFT, more studies are necessary to refine our understanding and treatment approaches. |
format | Online Article Text |
id | pubmed-10491928 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-104919282023-09-10 Gluteal Mystery: A Case Report of Superficial CD34-Positive Fibroblastic Tumor Ba-shammakh, Saleh A Almaletti, Motasem Hasan, Mohammad M Hijazi, Eman Cureus Pathology The case at hand involves a 25-year-old woman suffering from a gradual enlargement of a gluteal mass over a five-year period. This rare medical condition is classified as superficial CD34-positive fibroblastic tumor (SCPFT), an intermediate form of mesenchymal malignancy, originally identified in medical literature in 2014. Initial physical examination revealed a 10 x 10 cm lump in the right upper gluteal region. Magnetic resonance imaging demonstrated a well-circumscribed lesion within the right gluteus maximus muscle. The patient had the lump removed surgically. Examination under a microscope revealed tumor cells with extensive pleomorphism, high cytokeratin (CK) and CD34 positivity, and a low Ki67 index, all of which are consistent with SCPFT. Postoperatively, the patient showed marked improvement, and ongoing monitoring was initiated due to the potential for local recurrence. This case reinforces the importance of considering SCPFT in the differential diagnosis of soft tissue masses, emphasizing the role of immunohistochemical staining in reaching a correct diagnosis. Given the rarity of SCPFT, more studies are necessary to refine our understanding and treatment approaches. Cureus 2023-08-09 /pmc/articles/PMC10491928/ /pubmed/37692690 http://dx.doi.org/10.7759/cureus.43236 Text en Copyright © 2023, Ba-shammakh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Ba-shammakh, Saleh A Almaletti, Motasem Hasan, Mohammad M Hijazi, Eman Gluteal Mystery: A Case Report of Superficial CD34-Positive Fibroblastic Tumor |
title | Gluteal Mystery: A Case Report of Superficial CD34-Positive Fibroblastic Tumor |
title_full | Gluteal Mystery: A Case Report of Superficial CD34-Positive Fibroblastic Tumor |
title_fullStr | Gluteal Mystery: A Case Report of Superficial CD34-Positive Fibroblastic Tumor |
title_full_unstemmed | Gluteal Mystery: A Case Report of Superficial CD34-Positive Fibroblastic Tumor |
title_short | Gluteal Mystery: A Case Report of Superficial CD34-Positive Fibroblastic Tumor |
title_sort | gluteal mystery: a case report of superficial cd34-positive fibroblastic tumor |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491928/ https://www.ncbi.nlm.nih.gov/pubmed/37692690 http://dx.doi.org/10.7759/cureus.43236 |
work_keys_str_mv | AT bashammakhsaleha glutealmysteryacasereportofsuperficialcd34positivefibroblastictumor AT almalettimotasem glutealmysteryacasereportofsuperficialcd34positivefibroblastictumor AT hasanmohammadm glutealmysteryacasereportofsuperficialcd34positivefibroblastictumor AT hijazieman glutealmysteryacasereportofsuperficialcd34positivefibroblastictumor |