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Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50%

INTRODUCTION: The efficacy of catheter ablation in patients with low cardiac function has been previously reported; however, only a few studies have included mid-range ejection fraction (mrEF). This study aimed to evaluate the efficacy and safety of atrial fibrillation (AF) ablation in patients with...

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Autores principales: Sakamoto, Yusuke, Osanai, Hiroyuki, Sakai, Yuichiro, Sogo, Yoshiki, Tanaka, Yuki, Hiramatsu, Shotaro, Matsumoto, Hikari, Tomooka, Ken, Arai, Kenji, Watanabe, Takashi, Ohguchi, Shioh, Kanbara, Takahiro, Nakashima, Yoshihito, Asano, Hiroshi, Ajioka, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491960/
https://www.ncbi.nlm.nih.gov/pubmed/37385589
http://dx.doi.org/10.1016/j.ipej.2023.06.004
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author Sakamoto, Yusuke
Osanai, Hiroyuki
Sakai, Yuichiro
Sogo, Yoshiki
Tanaka, Yuki
Hiramatsu, Shotaro
Matsumoto, Hikari
Tomooka, Ken
Arai, Kenji
Watanabe, Takashi
Ohguchi, Shioh
Kanbara, Takahiro
Nakashima, Yoshihito
Asano, Hiroshi
Ajioka, Masayoshi
author_facet Sakamoto, Yusuke
Osanai, Hiroyuki
Sakai, Yuichiro
Sogo, Yoshiki
Tanaka, Yuki
Hiramatsu, Shotaro
Matsumoto, Hikari
Tomooka, Ken
Arai, Kenji
Watanabe, Takashi
Ohguchi, Shioh
Kanbara, Takahiro
Nakashima, Yoshihito
Asano, Hiroshi
Ajioka, Masayoshi
author_sort Sakamoto, Yusuke
collection PubMed
description INTRODUCTION: The efficacy of catheter ablation in patients with low cardiac function has been previously reported; however, only a few studies have included mid-range ejection fraction (mrEF). This study aimed to evaluate the efficacy and safety of atrial fibrillation (AF) ablation in patients with left ventricular ejection fraction (LVEF) < 50%. METHODS: This study retrospectively analyzed 79 patients (reduced ejection fraction [rEF]/mrEF, 38/41; paroxysmal/persistent, 37/42; heart failure hospitalizations within one year before ablation, 36 [45.6%]) who underwent the first ablation procedure at our hospital from April 2017 to December 2021. Radiofrequency ablation and cryoablation were performed for 69 and 10 patients, respectively. RESULTS: Complications included pacemaker implantation for postoperative sick sinus syndrome in one patient and inguinal hematoma in one patient. Regarding efficacy, there were significant postoperative improvements in echocardiographic data, blood test values, and diuretic use. After a mean follow-up of 60 months, 86.1% patients had no AF recurrence. There were 9 heart failure hospitalizations (11.4%) and 5 all-cause deaths (6.3%); no significant differences were found between the rEF and mrEF groups. No significant predictors of AF recurrence were found in preoperative patient characteristics. CONCLUSION: AF ablation in patients with LVEF <50% significantly improved cardiac and renal functions with few complications, resulting in a high non-recurrence rate and reduced heart failure.
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spelling pubmed-104919602023-09-10 Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50% Sakamoto, Yusuke Osanai, Hiroyuki Sakai, Yuichiro Sogo, Yoshiki Tanaka, Yuki Hiramatsu, Shotaro Matsumoto, Hikari Tomooka, Ken Arai, Kenji Watanabe, Takashi Ohguchi, Shioh Kanbara, Takahiro Nakashima, Yoshihito Asano, Hiroshi Ajioka, Masayoshi Indian Pacing Electrophysiol J Original Article INTRODUCTION: The efficacy of catheter ablation in patients with low cardiac function has been previously reported; however, only a few studies have included mid-range ejection fraction (mrEF). This study aimed to evaluate the efficacy and safety of atrial fibrillation (AF) ablation in patients with left ventricular ejection fraction (LVEF) < 50%. METHODS: This study retrospectively analyzed 79 patients (reduced ejection fraction [rEF]/mrEF, 38/41; paroxysmal/persistent, 37/42; heart failure hospitalizations within one year before ablation, 36 [45.6%]) who underwent the first ablation procedure at our hospital from April 2017 to December 2021. Radiofrequency ablation and cryoablation were performed for 69 and 10 patients, respectively. RESULTS: Complications included pacemaker implantation for postoperative sick sinus syndrome in one patient and inguinal hematoma in one patient. Regarding efficacy, there were significant postoperative improvements in echocardiographic data, blood test values, and diuretic use. After a mean follow-up of 60 months, 86.1% patients had no AF recurrence. There were 9 heart failure hospitalizations (11.4%) and 5 all-cause deaths (6.3%); no significant differences were found between the rEF and mrEF groups. No significant predictors of AF recurrence were found in preoperative patient characteristics. CONCLUSION: AF ablation in patients with LVEF <50% significantly improved cardiac and renal functions with few complications, resulting in a high non-recurrence rate and reduced heart failure. Elsevier 2023-06-27 /pmc/articles/PMC10491960/ /pubmed/37385589 http://dx.doi.org/10.1016/j.ipej.2023.06.004 Text en © 2023 Indian Heart Rhythm Society. Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Sakamoto, Yusuke
Osanai, Hiroyuki
Sakai, Yuichiro
Sogo, Yoshiki
Tanaka, Yuki
Hiramatsu, Shotaro
Matsumoto, Hikari
Tomooka, Ken
Arai, Kenji
Watanabe, Takashi
Ohguchi, Shioh
Kanbara, Takahiro
Nakashima, Yoshihito
Asano, Hiroshi
Ajioka, Masayoshi
Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50%
title Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50%
title_full Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50%
title_fullStr Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50%
title_full_unstemmed Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50%
title_short Efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50%
title_sort efficacy and safety of atrial fibrillation ablation in heart failure patients with left ventricular ejection fraction less than 50%
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491960/
https://www.ncbi.nlm.nih.gov/pubmed/37385589
http://dx.doi.org/10.1016/j.ipej.2023.06.004
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