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Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer

INTRODUCTION: Gastric cancer (GC)is the third leading cause of cancer-related deaths in China and immunotherapy emerging as a revolutionary treatment for GC recently. Tumor mutational burden (TMB) is a predictive biomarker of immunotherapy in multiple cancers. However, the prognostic significance an...

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Detalles Bibliográficos
Autores principales: Cheng, Yanan, Bu, Dechao, Zhang, Qiaoling, Sun, Rebecca, Lyle, Stephen, Zhao, Gang, Dong, Li, Li, Hui, Zhao, Yi, Yu, Jinpu, Hao, Xishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491970/
https://www.ncbi.nlm.nih.gov/pubmed/36351537
http://dx.doi.org/10.1016/j.jare.2022.10.019