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Expression of the odd-2 Gene in C. elegans

The odd-2 gene in C. elegans is an orthologue of the odd-skipped gene in Drosophila and the odd-skipped related genes in mammals. The mammalian genes have been shown to be expressed in a variety of tissues and cancers. It was previously reported that ODD-2 is expressed in the intestine and shows som...

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Autores principales: Charnysh, Elizabeth, Strohmaier, Keith R., Rothman, Joel H., Groth, Amy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492040/
https://www.ncbi.nlm.nih.gov/pubmed/37692086
http://dx.doi.org/10.17912/micropub.biology.000967
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author Charnysh, Elizabeth
Strohmaier, Keith R.
Rothman, Joel H.
Groth, Amy C.
author_facet Charnysh, Elizabeth
Strohmaier, Keith R.
Rothman, Joel H.
Groth, Amy C.
author_sort Charnysh, Elizabeth
collection PubMed
description The odd-2 gene in C. elegans is an orthologue of the odd-skipped gene in Drosophila and the odd-skipped related genes in mammals. The mammalian genes have been shown to be expressed in a variety of tissues and cancers. It was previously reported that ODD-2 is expressed in the intestine and shows some expression outside of the intestine in the tail region. Using a partial ODD-2 ::GFP fusion, we hypothesize that the expression outside of the intestine may be in rectal gland cells, and we also report that ODD-2 may be expressed in the germline sheath cells.
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spelling pubmed-104920402023-09-10 Expression of the odd-2 Gene in C. elegans Charnysh, Elizabeth Strohmaier, Keith R. Rothman, Joel H. Groth, Amy C. MicroPubl Biol New Finding The odd-2 gene in C. elegans is an orthologue of the odd-skipped gene in Drosophila and the odd-skipped related genes in mammals. The mammalian genes have been shown to be expressed in a variety of tissues and cancers. It was previously reported that ODD-2 is expressed in the intestine and shows some expression outside of the intestine in the tail region. Using a partial ODD-2 ::GFP fusion, we hypothesize that the expression outside of the intestine may be in rectal gland cells, and we also report that ODD-2 may be expressed in the germline sheath cells. Caltech Library 2023-08-25 /pmc/articles/PMC10492040/ /pubmed/37692086 http://dx.doi.org/10.17912/micropub.biology.000967 Text en Copyright: © 2023 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle New Finding
Charnysh, Elizabeth
Strohmaier, Keith R.
Rothman, Joel H.
Groth, Amy C.
Expression of the odd-2 Gene in C. elegans
title Expression of the odd-2 Gene in C. elegans
title_full Expression of the odd-2 Gene in C. elegans
title_fullStr Expression of the odd-2 Gene in C. elegans
title_full_unstemmed Expression of the odd-2 Gene in C. elegans
title_short Expression of the odd-2 Gene in C. elegans
title_sort expression of the odd-2 gene in c. elegans
topic New Finding
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492040/
https://www.ncbi.nlm.nih.gov/pubmed/37692086
http://dx.doi.org/10.17912/micropub.biology.000967
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