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mRNA splicing is modulated by intronic microRNAs

Splicing of transcripts is catalyzed by the spliceosome, a mega-complex consisting of hundreds of proteins and five snRNAs, which employs direct interactions. When U1 snRNA forms high-affinity binding, namely more than eight base pairs, with the 5′SS, the result is usually a suppressing effect on th...

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Detalles Bibliográficos
Autores principales:	Farberov, Luba, Weissglas-Volkov, Daphna, Shapira, Guy, Zoabi, Yazeed, Schiff, Chen, Kloeckener-Gruissem, Barbara, Neidhardt, John, Shomron, Noam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492213/ https://www.ncbi.nlm.nih.gov/pubmed/37692287 http://dx.doi.org/10.1016/j.isci.2023.107723

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