CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis

Septic acute kidney injury (S-AKI), the most common type of acute kidney injury (AKI), is intimately related to pyroptosis and oxidative stress in its pathogenesis. Carboxy-terminus of Hsc70-interacting protein (CHIP), a U-box E3 ligase, modulates oxidative stress by degrading its targeted proteins....

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Deng, Zebin, Wang, Yilong, Zheng, Xiaoping, Zhou, Lizhi, Yan, Shu, Wang, Yinhuai, Dai, Yingbo, Kanwar, Yashpal.S., Deng, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492219/
https://www.ncbi.nlm.nih.gov/pubmed/37692286
http://dx.doi.org/10.1016/j.isci.2023.107762

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