A Double-Blind, Randomized, Placebo-controlled Trial of Long-Term Doxycycline Therapy on Exacerbation Rate in Patients with Stable Chronic Obstructive Pulmonary Disease

RATIONALE: Chronic obstructive pulmonary disease (COPD) exacerbations are a major cause of morbidity and mortality, and preventing them is a key treatment target. Long-term macrolide treatment is effective at reducing exacerbations, but there is a paucity of evidence for other antibiotic classes. OB...

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Detalles Bibliográficos
Autores principales: Allinson, James P., Vlies, Ben H., Brill, Simon E., Law, Martin, Burnside, Girvan, Finney, Lydia J., Alves-Moreira, Luana, Donaldson, Gavin C., Calverley, Peter M. A., Walker, Paul P., Wedzicha, Jadwiga A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492249/
https://www.ncbi.nlm.nih.gov/pubmed/37450935
http://dx.doi.org/10.1164/rccm.202212-2287OC

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