circEIF3I facilitates the recruitment of SMAD3 to early endosomes to promote TGF-β signalling pathway-mediated activation of MMPs in pancreatic cancer

BACKGROUND: Among digestive tract tumours, pancreatic ductal adenocarcinoma (PDAC) shows the highest mortality trend. Moreover, although PDAC metastasis remains a leading cause of cancer-related deaths, the biological mechanism is poorly understood. Recent evidence demonstrates that circular RNAs (c...

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Detalles Bibliográficos
Autores principales: Zhao, Zhongjie, Yang, Wenbo, Kong, Rui, Zhang, Yangyang, Li, Le, Song, Zengfu, Chen, Hongze, Luo, Yan, Zhang, Tao, Cheng, Chundong, Li, Guanqun, Liu, Danxi, Geng, Xinglong, Chen, Hua, Wang, Yongwei, Pan, Shangha, Hu, Jisheng, Sun, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492306/
https://www.ncbi.nlm.nih.gov/pubmed/37689715
http://dx.doi.org/10.1186/s12943-023-01847-2

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