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Neddylation inhibitor MLN4924 sensitizes head and neck squamous carcinoma cells to (S)-10-hydroxycamptothecin

Head and neck squamous carcinoma (HNSCC) is the seventh most common cancer worldwide. Targeted therapeutic drugs for HNSCC are still being explored. Among them, (S)-10-hydroxycamptothecin (10-HCPT), a specific inhibitor of TOP1, functions by DNA double-strand breaks that can inhibit DNA replication...

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Detalles Bibliográficos
Autores principales:	Gu, Shanshan, Lin, Chen, Li, Yanguo, Wei, Zhengyu, cao, Bing, Shen, Zhisen, Deng, Hongxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492332/ https://www.ncbi.nlm.nih.gov/pubmed/37689760 http://dx.doi.org/10.1186/s40001-023-01289-y

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