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Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication ‘Jambavasa’ Used in the Treatment of Type 2 Diabetes Mellitus

Erythema multiforme (EM) is a rare immune-mediated condition that can manifest as cutaneous, mucosal, or both types of lesions. The target lesion, with concentric zones of color change, is a cutaneous feature that is typical of this illness. Despite the fact that a number of factors can lead to EM,...

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Autores principales: Gemnani, Rinkle, Mahajan, Satish, Saboo, Keyur, Pradeep, Utkarsh, Gupta, Aman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492666/
https://www.ncbi.nlm.nih.gov/pubmed/37701014
http://dx.doi.org/10.7759/cureus.43306
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author Gemnani, Rinkle
Mahajan, Satish
Saboo, Keyur
Pradeep, Utkarsh
Gupta, Aman
author_facet Gemnani, Rinkle
Mahajan, Satish
Saboo, Keyur
Pradeep, Utkarsh
Gupta, Aman
author_sort Gemnani, Rinkle
collection PubMed
description Erythema multiforme (EM) is a rare immune-mediated condition that can manifest as cutaneous, mucosal, or both types of lesions. The target lesion, with concentric zones of color change, is a cutaneous feature that is typical of this illness. Despite the fact that a number of factors can lead to EM, the most common being Herpes simplex virus (HSV) infection, drug-induced EM is a rare entity. As disease severity and mucosal involvement vary across individuals, treatment should be optimized for each patient, considering the risk versus benefit ratio. To distinguish EM from other clinical imitators and to confirm the diagnosis, histopathologic tests and other laboratory procedures may be utilized. Our patient presented with symptoms suggestive of a viral infection, such as fever and rash, but the RTPCR report for various viral infections came out to be negative, hence indicative of the diagnosis of drug-induced erythema multiforme.
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spelling pubmed-104926662023-09-11 Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication ‘Jambavasa’ Used in the Treatment of Type 2 Diabetes Mellitus Gemnani, Rinkle Mahajan, Satish Saboo, Keyur Pradeep, Utkarsh Gupta, Aman Cureus Dermatology Erythema multiforme (EM) is a rare immune-mediated condition that can manifest as cutaneous, mucosal, or both types of lesions. The target lesion, with concentric zones of color change, is a cutaneous feature that is typical of this illness. Despite the fact that a number of factors can lead to EM, the most common being Herpes simplex virus (HSV) infection, drug-induced EM is a rare entity. As disease severity and mucosal involvement vary across individuals, treatment should be optimized for each patient, considering the risk versus benefit ratio. To distinguish EM from other clinical imitators and to confirm the diagnosis, histopathologic tests and other laboratory procedures may be utilized. Our patient presented with symptoms suggestive of a viral infection, such as fever and rash, but the RTPCR report for various viral infections came out to be negative, hence indicative of the diagnosis of drug-induced erythema multiforme. Cureus 2023-08-10 /pmc/articles/PMC10492666/ /pubmed/37701014 http://dx.doi.org/10.7759/cureus.43306 Text en Copyright © 2023, Gemnani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Gemnani, Rinkle
Mahajan, Satish
Saboo, Keyur
Pradeep, Utkarsh
Gupta, Aman
Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication ‘Jambavasa’ Used in the Treatment of Type 2 Diabetes Mellitus
title Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication ‘Jambavasa’ Used in the Treatment of Type 2 Diabetes Mellitus
title_full Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication ‘Jambavasa’ Used in the Treatment of Type 2 Diabetes Mellitus
title_fullStr Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication ‘Jambavasa’ Used in the Treatment of Type 2 Diabetes Mellitus
title_full_unstemmed Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication ‘Jambavasa’ Used in the Treatment of Type 2 Diabetes Mellitus
title_short Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication ‘Jambavasa’ Used in the Treatment of Type 2 Diabetes Mellitus
title_sort erythema multiforme: unveiling the unusual effect of an ayurvedic medication ‘jambavasa’ used in the treatment of type 2 diabetes mellitus
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492666/
https://www.ncbi.nlm.nih.gov/pubmed/37701014
http://dx.doi.org/10.7759/cureus.43306
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