Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

The microvasculature plays a key role in tissue perfusion and exchange of gases and metabolites. In this study we use human blood vessel organoids (BVOs) as a model of the microvasculature. BVOs fully recapitulate key features of the human microvasculature, including the reliance of mature endotheli...

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Detalles Bibliográficos
Autores principales: Romeo, Sara G., Secco, Ilaria, Schneider, Edoardo, Reumiller, Christina M., Santos, Celio X. C., Zoccarato, Anna, Musale, Vishal, Pooni, Aman, Yin, Xiaoke, Theofilatos, Konstantinos, Trevelin, Silvia Cellone, Zeng, Lingfang, Mann, Giovanni E., Pathak, Varun, Harkin, Kevin, Stitt, Alan W., Medina, Reinhold J., Margariti, Andriana, Mayr, Manuel, Shah, Ajay M., Giacca, Mauro, Zampetaki, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492781/
https://www.ncbi.nlm.nih.gov/pubmed/37689702
http://dx.doi.org/10.1038/s41467-023-41326-2

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