Phosphorylation at tyrosine 317 and 508 are crucial for PIK3CA/p110α to promote CRC tumorigenesis

BACKGROUND: PI3K/AKT signaling pathway plays important role in tumorigenesis of human cancer. Protein phosphorylation is crucial for signaling transduction of this pathway. PIK3CA, encoding the catalytic subunit p110α of PI3K complex, is one of the most frequently mutated oncogenes in human cancers....

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ting, Sun, Longci, Chen, Chengkun, Zhang, Yingchao, He, Baoyu, Zhang, Yanhua, Wang, Zhenghe, Xue, Hanbing, Hao, Yujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493024/
https://www.ncbi.nlm.nih.gov/pubmed/37689735
http://dx.doi.org/10.1186/s13578-023-01102-7

Ejemplares similares

Ejemplares similares