A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis?

We report a case of 32-year-old patient who presented with painless erythematous plaque gradually ulcerated for 9 years. He had a history of pulmonary tuberculosis 12 years ago and was cured by the treatment of 2HRZE/4HR. The laboratory examination of t-spot and PPD skin test was positive. Histopath...

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Autores principales: Yang, Xianhong, Ren, Yunlin, Liu, Huachu, Ten, Yan, Ding, Yang, Fan, Shasha, Tao, Xiaohua, Lu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493093/
https://www.ncbi.nlm.nih.gov/pubmed/37701061
http://dx.doi.org/10.2147/CCID.S422546
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author Yang, Xianhong
Ren, Yunlin
Liu, Huachu
Ten, Yan
Ding, Yang
Fan, Shasha
Tao, Xiaohua
Lu, Wei
author_facet Yang, Xianhong
Ren, Yunlin
Liu, Huachu
Ten, Yan
Ding, Yang
Fan, Shasha
Tao, Xiaohua
Lu, Wei
author_sort Yang, Xianhong
collection PubMed
description We report a case of 32-year-old patient who presented with painless erythematous plaque gradually ulcerated for 9 years. He had a history of pulmonary tuberculosis 12 years ago and was cured by the treatment of 2HRZE/4HR. The laboratory examination of t-spot and PPD skin test was positive. Histopathology examinations of left cervical lymph node as well as skin revealed granulomatous inflammation with caseous necrosis. A diagnosis of scrofuloderma was made. Negative sputum culture and chest CT scan results excluded pulmonary tuberculosis. The patient was treated with a standard antituberculosis therapy and recovered well after 5 months’ follow-up. Scrofuloderma is a rare manifestation of mycobacterial infection. Early diagnosis and treatment are very important.
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spelling pubmed-104930932023-09-11 A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis? Yang, Xianhong Ren, Yunlin Liu, Huachu Ten, Yan Ding, Yang Fan, Shasha Tao, Xiaohua Lu, Wei Clin Cosmet Investig Dermatol Case Report We report a case of 32-year-old patient who presented with painless erythematous plaque gradually ulcerated for 9 years. He had a history of pulmonary tuberculosis 12 years ago and was cured by the treatment of 2HRZE/4HR. The laboratory examination of t-spot and PPD skin test was positive. Histopathology examinations of left cervical lymph node as well as skin revealed granulomatous inflammation with caseous necrosis. A diagnosis of scrofuloderma was made. Negative sputum culture and chest CT scan results excluded pulmonary tuberculosis. The patient was treated with a standard antituberculosis therapy and recovered well after 5 months’ follow-up. Scrofuloderma is a rare manifestation of mycobacterial infection. Early diagnosis and treatment are very important. Dove 2023-09-06 /pmc/articles/PMC10493093/ /pubmed/37701061 http://dx.doi.org/10.2147/CCID.S422546 Text en © 2023 Yang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Yang, Xianhong
Ren, Yunlin
Liu, Huachu
Ten, Yan
Ding, Yang
Fan, Shasha
Tao, Xiaohua
Lu, Wei
A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis?
title A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis?
title_full A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis?
title_fullStr A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis?
title_full_unstemmed A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis?
title_short A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis?
title_sort chronic multiple site of scrofuloderma: is it reactivation or treatment failure of tuberculosis?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493093/
https://www.ncbi.nlm.nih.gov/pubmed/37701061
http://dx.doi.org/10.2147/CCID.S422546
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