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Claudin18.2 bispecific T cell engager armed oncolytic virus enhances antitumor effects against pancreatic cancer

Bispecific T cell engagers (BiTEs) represent a promising immunotherapy, but their efficacy against immunologically cold tumors such as pancreatic ductal adenocarcinoma remains unclear. Oncolytic viruses (OVs) can transform the immunosuppressive tumor microenvironment into the active state and also s...

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Detalles Bibliográficos
Autores principales: Liu, Shiyu, Li, Fan, Deng, Li, Ma, Qiongqiong, Lu, Wenyi, Zhao, Zhuoqian, Liu, Huanzhen, Zhou, Yixuan, Hu, Manli, Wang, Hui, Yan, Yingbin, Zhao, Mingfeng, Zhang, Hongkai, Du, Mingjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493249/
https://www.ncbi.nlm.nih.gov/pubmed/37701851
http://dx.doi.org/10.1016/j.omto.2023.08.011

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