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Neoplasms of the appendix: Single institution and ten-year experiences results

BACKGROUND: Appendix neoplasms are rare tumors of the gastrointestinal system. Appendiceal adenocarcinoma, appendiceal mucinous neoplasm, and neuroendocrine tumors (NETs) are the most encountered appendix-related neoplasms. The patients are usually got diagnosed after histopathological examination....

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Autores principales: Yıldırım, Emine, Kegin, Murat, Özdemir, Muhammed, Bektaş, Sibel, Pelen, Zekeriya, Er, Muzaffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493524/
https://www.ncbi.nlm.nih.gov/pubmed/35485573
http://dx.doi.org/10.14744/tjtes.2021.86032
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author Yıldırım, Emine
Kegin, Murat
Özdemir, Muhammed
Bektaş, Sibel
Pelen, Zekeriya
Er, Muzaffer
author_facet Yıldırım, Emine
Kegin, Murat
Özdemir, Muhammed
Bektaş, Sibel
Pelen, Zekeriya
Er, Muzaffer
author_sort Yıldırım, Emine
collection PubMed
description BACKGROUND: Appendix neoplasms are rare tumors of the gastrointestinal system. Appendiceal adenocarcinoma, appendiceal mucinous neoplasm, and neuroendocrine tumors (NETs) are the most encountered appendix-related neoplasms. The patients are usually got diagnosed after histopathological examination. This study aimed to explore the epidemiology, pathological subtypes, and treatment modalities of appendix neoplasms. METHODS: A retrospective examination was made with 2821 patients who underwent appendectomy between April 2010 and August 2020. Demographic, clinical, radiological, surgical findings, and histopathological results were collected from the patient files. RESULTS: Appendix neoplasms were detected in 1.06% of the patients included in the study. The mean age was 44.6±17.5 (17–83) years. Eight NETs, seven adenocarcinomas, fourteen mucinous neoplasms, and one neuroma were diagnosed with patients. CONCLUSION: Appendiceal neoplasms are generally asymptomatic and often diagnosed with postoperative histopathological examination. If the result is adenocarcinoma, right hemicolectomy recommends. Treatment of NETs depends on factors such as tumor size, location, mesoappendix invasion, and lymph node involvement. In the presence of mucinous neoplasm, surgical intervention is determined according to the pathological subtype and involvement of mesoappendix. The need for additional surgical intervention or medical treatment for patients with tumor, histopathological results must be followed carefully after appendectomy.
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spelling pubmed-104935242023-09-12 Neoplasms of the appendix: Single institution and ten-year experiences results Yıldırım, Emine Kegin, Murat Özdemir, Muhammed Bektaş, Sibel Pelen, Zekeriya Er, Muzaffer Ulus Travma Acil Cerrahi Derg Original Article BACKGROUND: Appendix neoplasms are rare tumors of the gastrointestinal system. Appendiceal adenocarcinoma, appendiceal mucinous neoplasm, and neuroendocrine tumors (NETs) are the most encountered appendix-related neoplasms. The patients are usually got diagnosed after histopathological examination. This study aimed to explore the epidemiology, pathological subtypes, and treatment modalities of appendix neoplasms. METHODS: A retrospective examination was made with 2821 patients who underwent appendectomy between April 2010 and August 2020. Demographic, clinical, radiological, surgical findings, and histopathological results were collected from the patient files. RESULTS: Appendix neoplasms were detected in 1.06% of the patients included in the study. The mean age was 44.6±17.5 (17–83) years. Eight NETs, seven adenocarcinomas, fourteen mucinous neoplasms, and one neuroma were diagnosed with patients. CONCLUSION: Appendiceal neoplasms are generally asymptomatic and often diagnosed with postoperative histopathological examination. If the result is adenocarcinoma, right hemicolectomy recommends. Treatment of NETs depends on factors such as tumor size, location, mesoappendix invasion, and lymph node involvement. In the presence of mucinous neoplasm, surgical intervention is determined according to the pathological subtype and involvement of mesoappendix. The need for additional surgical intervention or medical treatment for patients with tumor, histopathological results must be followed carefully after appendectomy. Kare Publishing 2022-03-01 /pmc/articles/PMC10493524/ /pubmed/35485573 http://dx.doi.org/10.14744/tjtes.2021.86032 Text en Copyright © 2022 Turkish Journal of Trauma and Emergency Surgery https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Original Article
Yıldırım, Emine
Kegin, Murat
Özdemir, Muhammed
Bektaş, Sibel
Pelen, Zekeriya
Er, Muzaffer
Neoplasms of the appendix: Single institution and ten-year experiences results
title Neoplasms of the appendix: Single institution and ten-year experiences results
title_full Neoplasms of the appendix: Single institution and ten-year experiences results
title_fullStr Neoplasms of the appendix: Single institution and ten-year experiences results
title_full_unstemmed Neoplasms of the appendix: Single institution and ten-year experiences results
title_short Neoplasms of the appendix: Single institution and ten-year experiences results
title_sort neoplasms of the appendix: single institution and ten-year experiences results
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493524/
https://www.ncbi.nlm.nih.gov/pubmed/35485573
http://dx.doi.org/10.14744/tjtes.2021.86032
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