Efficacy, safety, and correlative biomarkers of bintrafusp alfa in recurrent or metastatic nasopharyngeal cancer patients: a phase II clinical trial

BACKGROUND: The strategy of dual blockade of TGF-β and PD-L1 pathways has not been previously tested in platinum-refractory recurrent or metastatic nasopharyngeal cancer (R/M NPC) patients. This study aimed to evaluate the safety and efficacy of bintrafusp alfa in refractory R/M NPC patients. METHOD...

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Detalles Bibliográficos
Autores principales: Chiang, Chi Leung, Lam, Tai Chung, Li, James Chun Bong, Chan, Kenneth Sik Kwan, El Helali, Aya, Lee, Yolanda Yim Ping, Law, Laalaa Hiu Ting, Zheng, Danyang, Lo, Anthony Wing Ip, Kam, Ngar Woon, Li, Wing Sum, Cheung, Alice Ka Wai, Chow, James Chung Hang, Chan, Sunny Po Chung, Lai, Jessica Wing Yu, Lee, Sarah Wai Man, Kong, Feng-Ming (Spring), Ng, Wai Tong, Kwong, Dora Lai Wan, Lee, Anne Wing Mui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493598/
https://www.ncbi.nlm.nih.gov/pubmed/37701718
http://dx.doi.org/10.1016/j.lanwpc.2023.100898

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