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Histone demethylase KDM6A coordinating with KMT2B regulates self-renewal and chemoresistance of non-small cell lung cancer stem cells

BACKGROUND AND AIMS: Wnt signaling is essential for the maintenance of cancer stem cells (CSCs), but mutations in the β-catenin and APC genes are less common in non-small cell lung carcinoma (NSCLC). Thus, the mechanism underlying the constitutive activation of Wnt signaling in lung CSCs is still un...

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Detalles Bibliográficos
Autores principales: Chen, Zhiwei, Qi, Yuwen, Shen, Jie, Chen, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493599/
https://www.ncbi.nlm.nih.gov/pubmed/37683307
http://dx.doi.org/10.1016/j.tranon.2023.101778