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Induction of metallothionein expression by supplementation of zinc induces resistance against platinum-based treatment in malignant pleural mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive tumor with a dismal prognosis. Currently, multimodality treatment including chemotherapy with cisplatin or carboplatin in combination with pemetrexed offers the best options. Detoxification of heavy metals in the cell by metallothione...

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Detalles Bibliográficos
Autores principales:	Wyrich, Martine, Ohlig, Henning, Wessolly, Michael, Mairinger, Elena, Steinborn, Julia, Brcic, Luka, Hegedus, Balazs, Hager, Thomas, Greimelmaier, Kristina, Wohlschlaeger, Jeremias, Mairinger, Fabian D., Borchert, Sabrina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493783/ https://www.ncbi.nlm.nih.gov/pubmed/37701096 http://dx.doi.org/10.21037/tcr-22-2651

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