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Endovascular management of cerebral venous thrombosis: a tertiary-centre experience

BACKGROUND: Stroke related to cerebral venous thrombosis (CVT) is uncommon, with untoward lethal outcomes. Systemic anticoagulation is the treatment of choice. However, some patients can be resistant to this treatment. Endovascular management with thrombolysis and mechanical thrombectomy can be a vi...

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Autores principales: Palanisamy, Prabakaran, Kramadhari, Harshith, Badachi, Sagar, Kumar, G.G.Sharath, Aggipothu, Balakrishna, Mathew, Thomas, Sarma, G.R.K., Nadig, Raghunandan, Sucharitha, M.V., Deepalam, Saikanth Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493859/
https://www.ncbi.nlm.nih.gov/pubmed/37701176
http://dx.doi.org/10.5114/pjr.2023.130768
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author Palanisamy, Prabakaran
Kramadhari, Harshith
Badachi, Sagar
Kumar, G.G.Sharath
Aggipothu, Balakrishna
Mathew, Thomas
Sarma, G.R.K.
Nadig, Raghunandan
Sucharitha, M.V.
Deepalam, Saikanth Reddy
author_facet Palanisamy, Prabakaran
Kramadhari, Harshith
Badachi, Sagar
Kumar, G.G.Sharath
Aggipothu, Balakrishna
Mathew, Thomas
Sarma, G.R.K.
Nadig, Raghunandan
Sucharitha, M.V.
Deepalam, Saikanth Reddy
author_sort Palanisamy, Prabakaran
collection PubMed
description BACKGROUND: Stroke related to cerebral venous thrombosis (CVT) is uncommon, with untoward lethal outcomes. Systemic anticoagulation is the treatment of choice. However, some patients can be resistant to this treatment. Endovascular management with thrombolysis and mechanical thrombectomy can be a viable option in such cases. MATERIAL AND METHODS: We retrospectively reviewed the endovascular management used for CVT in 8 patients who failed to respond to standard anticoagulation therapy between December 2017 and December 2022 in our institute. Clinical profile, imaging parameters, endovascular procedure details, and outcomes in terms of angiographic findings and clinical follow-up were analysed. RESULTS: In this period, a total of 8 patients underwent mechanical thrombectomy. The procedure was successful in all cases (8/8 = 100%), and 50% of them showed near total/complete recanalization; Perforation of the cortical veins was noted in 2 cases (~25%). Among the 8 patients, one died (1/8 = 12.5%) due to cardiac aetiology; the remaining 7 patients (87.5%) showed good clinical outcome with a modified Rankin Scale score 0 to 2. CONCLUSION: Catheter-directed thrombolysis with mechanical thromboaspiration is a safe and effective treatment for cerebral venous sinus thrombosis not responding to anticoagulation.
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spelling pubmed-104938592023-09-12 Endovascular management of cerebral venous thrombosis: a tertiary-centre experience Palanisamy, Prabakaran Kramadhari, Harshith Badachi, Sagar Kumar, G.G.Sharath Aggipothu, Balakrishna Mathew, Thomas Sarma, G.R.K. Nadig, Raghunandan Sucharitha, M.V. Deepalam, Saikanth Reddy Pol J Radiol Original Paper BACKGROUND: Stroke related to cerebral venous thrombosis (CVT) is uncommon, with untoward lethal outcomes. Systemic anticoagulation is the treatment of choice. However, some patients can be resistant to this treatment. Endovascular management with thrombolysis and mechanical thrombectomy can be a viable option in such cases. MATERIAL AND METHODS: We retrospectively reviewed the endovascular management used for CVT in 8 patients who failed to respond to standard anticoagulation therapy between December 2017 and December 2022 in our institute. Clinical profile, imaging parameters, endovascular procedure details, and outcomes in terms of angiographic findings and clinical follow-up were analysed. RESULTS: In this period, a total of 8 patients underwent mechanical thrombectomy. The procedure was successful in all cases (8/8 = 100%), and 50% of them showed near total/complete recanalization; Perforation of the cortical veins was noted in 2 cases (~25%). Among the 8 patients, one died (1/8 = 12.5%) due to cardiac aetiology; the remaining 7 patients (87.5%) showed good clinical outcome with a modified Rankin Scale score 0 to 2. CONCLUSION: Catheter-directed thrombolysis with mechanical thromboaspiration is a safe and effective treatment for cerebral venous sinus thrombosis not responding to anticoagulation. Termedia Publishing House 2023-08-07 /pmc/articles/PMC10493859/ /pubmed/37701176 http://dx.doi.org/10.5114/pjr.2023.130768 Text en © Pol J Radiol 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Paper
Palanisamy, Prabakaran
Kramadhari, Harshith
Badachi, Sagar
Kumar, G.G.Sharath
Aggipothu, Balakrishna
Mathew, Thomas
Sarma, G.R.K.
Nadig, Raghunandan
Sucharitha, M.V.
Deepalam, Saikanth Reddy
Endovascular management of cerebral venous thrombosis: a tertiary-centre experience
title Endovascular management of cerebral venous thrombosis: a tertiary-centre experience
title_full Endovascular management of cerebral venous thrombosis: a tertiary-centre experience
title_fullStr Endovascular management of cerebral venous thrombosis: a tertiary-centre experience
title_full_unstemmed Endovascular management of cerebral venous thrombosis: a tertiary-centre experience
title_short Endovascular management of cerebral venous thrombosis: a tertiary-centre experience
title_sort endovascular management of cerebral venous thrombosis: a tertiary-centre experience
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493859/
https://www.ncbi.nlm.nih.gov/pubmed/37701176
http://dx.doi.org/10.5114/pjr.2023.130768
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