Obtaining Functional Proteomics Insights From Thermal Proteome Profiling Through Optimized Melt Shift Calculation and Statistical Analysis With InflectSSP

Thermal proteome profiling (TPP) is an invaluable tool for functional proteomics studies that has been shown to discover changes associated with protein–ligand, protein–protein, and protein–RNA interaction dynamics along with changes in protein stability resulting from cellular signaling. The increa...

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Detalles Bibliográficos
Autores principales: McCracken, Neil A., Liu, Hao, Runnebohm, Avery M., Wijeratne, H.R. Sagara, Wijeratne, Aruna B., Staschke, Kirk A., Mosley, Amber L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494267/
https://www.ncbi.nlm.nih.gov/pubmed/37562535
http://dx.doi.org/10.1016/j.mcpro.2023.100630

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