Next‐generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma

Glioblastoma (GBM) is an aggressive brain cancer with a poor prognosis. While surgical resection is the primary treatment, adjuvant temozolomide (TMZ) chemotherapy and radiotherapy only provide slight improvement in disease course and outcome. Unfortunately, most treated patients experience recurren...

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Detalles Bibliográficos
Autores principales: Yang, Chuanhe, He, Yali, Wang, Yinan, McKinnon, Peter J., Shahani, Vijay, Miller, Duane D., Pfeffer, Lawrence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494295/
https://www.ncbi.nlm.nih.gov/pubmed/37593885
http://dx.doi.org/10.1111/jcmm.17907

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