Cargando…

Low-dose LPS alleviates early brain injury after SAH by modulating microglial M1/M2 polarization via USP19/FOXO1/IL-10/IL-10R1 signaling

BACKGROUND: Low-dose lipopolysaccharide (LPS) protects against early brain injury (EBI) after subarachnoid hemorrhage (SAH). However, the mechanism underlying the neuroprotective roles of low-dose LPS remain largely undefined. METHODS: A SAH mice model was established and the pathological changes of...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Weihua, Zhang, Guibo, Liu, Chengyuan, Jin, Lide, Li, Xuehua, Yang, Shuaifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494318/
https://www.ncbi.nlm.nih.gov/pubmed/37672892
http://dx.doi.org/10.1016/j.redox.2023.102863